BDBM50177015 CHEMBL3814206::US10144715, Compound 19-1
SMILES CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O
InChI Key InChIKey=FPVIRRAMNBCEDK-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50177015
TargetOxysterols receptor LXR-alpha/LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Agonist activity at LXR in human THP1 cells assessed as upregulation of ABCA1 gene expression after 24 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Agonist activity at LXR in human HepG2 cells assessed as upregulation of SREBP1C gene expression after 24 hrs by RT-PCR analysisMore data for this Ligand-Target Pair